This Food Fact Sheet and others are available to download free of charge at .com/. rickets, osteoporosis, and osteomalacia). It is the suns ultraviolet rays that allow vitamin D to. Vitamin D deficiency is a cause of hyperparathyroidism and diseases related to impaired bone metabolism (e.g. Vitamin D plays a major role in calcium and phosphorus homeostasis. A small proportion of the 25(OH)D is further hydroxylated in the kidney, under direct regulation by parathyroid hormone and ionised calcium levels, to form the biologically-active calcitropic hormone 1,25-dihydroxyvitamin D. The more you can supplement your Vitamin D production from sun exposure with Vitamin D in your diet, the less sun exposure you need, and therefore the more sun damage you can avoid.
In the liver, vitamin D is hydroxylated to give 25(OH)D which also circulates as a complex with VDBP. Vitamin D is stored in adipose tissue and enters the circulation bound to vitamin D binding protein (VDBP) and albumin. Approximately 10 – 20 % of vitamin D is supplied through nutritional intake.
Main vitamin D sources are: UV exposure from sun which leads to Cholecalciferol production in the upper layers of the skin, foods such as fish, shellfish, mushrooms, vitamin D fortified foods (e.g. Of the two major forms Ergocalciferol (D2) and Cholecalciferol (D3), only vitamin D3 is synthesised by the body. Vitamin D is a fat-soluble steroid pro-hormone.
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